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cy5 5  (MedChemExpress)


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    MedChemExpress cy5 5
    Cy5 5, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 97 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy+d0924/Cy5%2E5/10__1016_slash_j__cej__2026__180787-64-0-4
    Average 97 stars, based on 97 article reviews
    cy5 5 - by Bioz Stars, 2026-09
    97/100 stars

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    Related Articles

    other:

    Article Title: Activated T-cell membrane-derived nanocargoes displaying multi-immune checkpoints for enhanced cancer immunotherapy
    Article Snippet: HY-D0924) were purchased from Med Chem Express.

    In Vivo:

    Article Title: PTEN as a prognostic factor for radiotherapy plus immunotherapy response in nasopharyngeal carcinoma
    Article Snippet: .. To evaluate the in vivo targeting capability of cell-derived exos towards tumor cells, Cy5.5-labeled exos (RT + IT exo, sh-NC + RT + IT exo, sh-PTEN + RT + IT exo) were prepared according to the manufacturer's instructions (HY-D0924, MCE). .. Post-injection, tissues from the tumor, heart, liver, spleen, lung, and kidney were dissected, and fluorescence images of the Cy5.5-labeled exos were captured using the IVIS Spectrum Imaging System (PerkinElmer, Waltham, MA, USA) [ , ].

    Article Title: PTEN as a prognostic factor for radiotherapy plus immunotherapy response in nasopharyngeal carcinoma.
    Article Snippet: .. To evaluate the in vivo targeting capability of cellderived exos towards tumor cells, Cy5.5-labeled exos (RT + IT exo, sh-NC + RT + IT exo, sh-PTEN + RT + IT exo) were prepared according to the manufacturer’s instructions (HY-D0924, MCE). .. Post-injection, tissues from the tumor, heart, liver, spleen, lung, and kidney were dissected, and fluorescence images of the Cy5.5labeled exos were captured using the IVIS Spectrum Imaging System (PerkinElmer, Waltham, MA, USA) [38, 39].



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    Gastrointestinal stability and biodistribution of RBNPs. (A – C) Hydrodynamic diameter (A), PDI (B), and zeta potential (C) of RBNPs incubated in PBS, SGF, or SIF. (D) In vitro cumulative release profiles of BBR from RBNPs in SGF and SIF over 48 h. (E – F) Representative in vivo fluorescence images (E) and quantification of radiant efficiency (F) in mice following oral administration of <t>Cy5.5@RBNPs</t> or free Cy5.5. (G) Ex vivo fluorescence images of major organs (H, heart; Lu, lung; Li, liver; S, spleen; K, kidney) and colons excised at indicated time points. (H) Quantification of radiant efficiency in major organs and colons. Data are presented as mean ± SD ( n = 3). Statistical significance was assessed by one-way ANOVA with Tukey's post hoc test, ∗∗∗∗ p < 0.0001; ns, not significant.
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    Gastrointestinal stability and biodistribution of RBNPs. (A – C) Hydrodynamic diameter (A), PDI (B), and zeta potential (C) of RBNPs incubated in PBS, SGF, or SIF. (D) In vitro cumulative release profiles of BBR from RBNPs in SGF and SIF over 48 h. (E – F) Representative in vivo fluorescence images (E) and quantification of radiant efficiency (F) in mice following oral administration of <t>Cy5.5@RBNPs</t> or free Cy5.5. (G) Ex vivo fluorescence images of major organs (H, heart; Lu, lung; Li, liver; S, spleen; K, kidney) and colons excised at indicated time points. (H) Quantification of radiant efficiency in major organs and colons. Data are presented as mean ± SD ( n = 3). Statistical significance was assessed by one-way ANOVA with Tukey's post hoc test, ∗∗∗∗ p < 0.0001; ns, not significant.
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    Image Search Results


    Gastrointestinal stability and biodistribution of RBNPs. (A – C) Hydrodynamic diameter (A), PDI (B), and zeta potential (C) of RBNPs incubated in PBS, SGF, or SIF. (D) In vitro cumulative release profiles of BBR from RBNPs in SGF and SIF over 48 h. (E – F) Representative in vivo fluorescence images (E) and quantification of radiant efficiency (F) in mice following oral administration of Cy5.5@RBNPs or free Cy5.5. (G) Ex vivo fluorescence images of major organs (H, heart; Lu, lung; Li, liver; S, spleen; K, kidney) and colons excised at indicated time points. (H) Quantification of radiant efficiency in major organs and colons. Data are presented as mean ± SD ( n = 3). Statistical significance was assessed by one-way ANOVA with Tukey's post hoc test, ∗∗∗∗ p < 0.0001; ns, not significant.

    Journal: Materials Today Bio

    Article Title: Self-assembled nanoparticles from Xiexin Decoction attenuate ulcerative colitis by targeting VDAC1-Mediated NLRP3 inflammasome activation

    doi: 10.1016/j.mtbio.2026.103078

    Figure Lengend Snippet: Gastrointestinal stability and biodistribution of RBNPs. (A – C) Hydrodynamic diameter (A), PDI (B), and zeta potential (C) of RBNPs incubated in PBS, SGF, or SIF. (D) In vitro cumulative release profiles of BBR from RBNPs in SGF and SIF over 48 h. (E – F) Representative in vivo fluorescence images (E) and quantification of radiant efficiency (F) in mice following oral administration of Cy5.5@RBNPs or free Cy5.5. (G) Ex vivo fluorescence images of major organs (H, heart; Lu, lung; Li, liver; S, spleen; K, kidney) and colons excised at indicated time points. (H) Quantification of radiant efficiency in major organs and colons. Data are presented as mean ± SD ( n = 3). Statistical significance was assessed by one-way ANOVA with Tukey's post hoc test, ∗∗∗∗ p < 0.0001; ns, not significant.

    Article Snippet: MedChemExpress supplied the Cy5.5 dye.

    Techniques: Zeta Potential Analyzer, Incubation, In Vitro, In Vivo, Fluorescence, Ex Vivo

    In vitro anti-inflammatory effects of XXD-based self-assembled nanoparticles. (A) Viability of RAW264.7 cells after 24-h treatment with XXD, XDNPs, or RBNPs, assessed using the CCK-8 assay. (B – C) Flow cytometry analysis of cellular uptake of Cy5.5-labeled RBNPs (Cy5.5@RBNPs) versus free Cy5.5. (D – E) Flow cytometry assessment of macrophage polarization (M1/M2) in RAW264.7 cells following treatment with the indicated formulations. (F – H) ELISA quantification of pro-inflammatory cytokines IL-1β (F), IL-6 (G), and TNF-α (H) in culture supernatants. (I) Nitric oxide (NO) production in the supernatant. (J) Confocal laser scanning microscopy (CLSM) images. (K – L) Flow cytometry analysis of intracellular reactive oxygen species (ROS). (M) Intracellular hydrogen peroxide (H 2 O 2 ) levels in LPS-stimulated RAW264.7 cells after treatment with the formulations. Data are presented as mean ± SD ( n = 3). Statistical significance was calculated using one-way ANOVA with Tukey's post hoc test. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001 versus the Model group; #### p < 0.0001 versus the Ctrl group.

    Journal: Materials Today Bio

    Article Title: Self-assembled nanoparticles from Xiexin Decoction attenuate ulcerative colitis by targeting VDAC1-Mediated NLRP3 inflammasome activation

    doi: 10.1016/j.mtbio.2026.103078

    Figure Lengend Snippet: In vitro anti-inflammatory effects of XXD-based self-assembled nanoparticles. (A) Viability of RAW264.7 cells after 24-h treatment with XXD, XDNPs, or RBNPs, assessed using the CCK-8 assay. (B – C) Flow cytometry analysis of cellular uptake of Cy5.5-labeled RBNPs (Cy5.5@RBNPs) versus free Cy5.5. (D – E) Flow cytometry assessment of macrophage polarization (M1/M2) in RAW264.7 cells following treatment with the indicated formulations. (F – H) ELISA quantification of pro-inflammatory cytokines IL-1β (F), IL-6 (G), and TNF-α (H) in culture supernatants. (I) Nitric oxide (NO) production in the supernatant. (J) Confocal laser scanning microscopy (CLSM) images. (K – L) Flow cytometry analysis of intracellular reactive oxygen species (ROS). (M) Intracellular hydrogen peroxide (H 2 O 2 ) levels in LPS-stimulated RAW264.7 cells after treatment with the formulations. Data are presented as mean ± SD ( n = 3). Statistical significance was calculated using one-way ANOVA with Tukey's post hoc test. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001 versus the Model group; #### p < 0.0001 versus the Ctrl group.

    Article Snippet: MedChemExpress supplied the Cy5.5 dye.

    Techniques: In Vitro, CCK-8 Assay, Flow Cytometry, Labeling, Enzyme-linked Immunosorbent Assay, Confocal Laser Scanning Microscopy